UYAMA, Yoshiaki: search on Z-Library

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1

Improving clinical trial sampling for future research – an international approach: outcomes and next steps from the DIA future use sampling workshop 2011

Warner, Amelia Wall, Bienfait, Karina L, Bledsoe, Marianna, Burckart, Gilbert, Flamion, Bruno, Knoppers, Bartha, Nelsen, Anita J, Rudman, Allen, Sieffert, Nicole J, Uyama, Yoshiaki

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 755 KB

english, 2013

2

Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts

Tadashi Sugiki, Taro Uyama, Masashi Toyoda, Hideo Morioka, Shoen Kume, Kenji Miyado, Kenji Matsumoto, Hirohisa Saito, Noriyuki Tsumaki, Yoriko Takahashi, Yoshiaki Toyama, Akihiro Umezawa

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 803 KB

english, 2007

3

Tetrahexylammonium ions increase Ca2+sensitivity of contraction of guinea-pig ileal smooth muscle

Yoshiaki Uyama, Katsuhiko Muraki, Michael P. Walsh, Yuji Imaizumi, Minoru Watanabe

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1994

Language:

english

File:

PDF, 869 KB

english, 1994

4

Potent vasoconstrictor actions of cyclopiazonic acid and thapsigargin on femoral arteries from spontaneously hypertensive rats

Yukiko Nomura, Masahisa Asano, Katsuaki Ito, Yoshiaki Uyama, Yuji Imaizumi, Minoru Watanabe

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 628 KB

english, 1997

5

Daily intake of food additives in Japan in five age groups estimated by the market basket method

Hajimu Ishiwata, Takashi Yamada, Nobuo Yoshiike, Motohiro Nishijima, Akio Kawamoto, Yoshiaki Uyama

Journal:

European Food Research and Technology

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

6

DCG-IV, a potent metabotropic glutamate receptor agonist, as an NMDA receptor agonist in the rat cortical slice

Yoshiaki Uyama, Michiko Ishida, Haruhiko Shinozaki

Journal:

Year:

1997

Language:

english

File:

PDF, 477 KB

english, 1997

7

Possible mechanism of the potent vasoconstrictor actions of ryanodine on femoral arteries from spontaneously hypertensive rats

Masahisa Asano, Miho Kuwako, Yukiko Nomura, Kaoru M. Ito, Katuaki Ito, Yoshiaki Uyama, Yuji Imaizumi, Minoru Watanabe

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.71 MB

english, 1996

8

Effects of cyclopiazonic acid, a novel Ca2+-ATPase inhibitor, on contractile responses in skinned ileal smooth muscle

Yoshiaki Uyama, Yuji Imaizumi, Minoru Watanabe

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.36 MB

english, 1992

9

Cyclopiazonic acid, an inhibitor of Ca2+-ATPase in sarcoplasmic reticulum, increases excitability in ileal smooth muscle

Yoshiaki Uyama, Yuji Imaizumi, Minoru Watanabe

Journal:

British Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.99 MB

english, 1993

10

Adaptive clinical trials for new drug applications in Japan

Yuki Ando, Akihiro Hirakawa, Yoshiaki Uyama

Journal:

European Neuropsychopharmacology

Year:

2011

Language:

english

File:

PDF, 157 KB

english, 2011

11

340 ‘Quisqualate effect’ revealed by an L-AP4 analog, glufosinate

Michiko Ishdia, Tomoko Saitoh, Yoshiaki Uyama, Haruhikq Shinozaki

Journal:

Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 112 KB

english, 1996

12

341 Regional differences in NMDA-like actions of DCG-IV in the rat

Yoshiaki Uyama, Tomoko Saitoh, Michiko Ishida, Haruhiko Shinozaki

Journal:

Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 112 KB

english, 1996

13

235 Role of metabotropic glutamate receptors on epileptiform activities in the rat cortical slice

Yoshiaki Uyama, Michiko Ishida, Haruhijo Shinozaki

Journal:

Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 109 KB

english, 1997

14

Pharmacogenetics in the evaluation of new drugs: a multiregional regulatory perspective

Maliepaard, Marc, Nofziger, Charity, Papaluca, Marisa, Zineh, Issam, Uyama, Yoshiaki, Prasad, Krishna, Grimstein, Christian, Pacanowski, Michael, Ehmann, Falk, Dossena, Silvia, Paulmichl, Markus

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 461 KB

english, 2013

15

Characteristics of pharmacogenomics/biomarker-guided clinical trials for regulatory approval of anti-cancer drugs in Japan

Ishiguro, Akihiro, Yagi, Satomi, Uyama, Yoshiaki

Journal:

Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 364 KB

english, 2013

16

Current Japanese regulatory situations of pharmacogenomics in drug administration

Ishiguro, Akihiro, Toyoshima, Satoshi, Uyama, Yoshiaki

Journal:

Expert Review of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

17

Regulatory perspective on remaining challenges for utilization of pharmacogenomics-guided drug developments

Otsubo, Yasuto, Ishiguro, Akihiro, Uyama, Yoshiaki

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 929 KB

english, 2013

18

Atypical Antipsychotics and the Risk of Hyperlipidemia: A Sequence Symmetry Analysis

Takeuchi, Yoshinori, Kajiyama, Kazuhiro, Ishiguro, Chieko, Uyama, Yoshiaki

Journal:

Year:

2015

Language:

english

File:

PDF, 651 KB

english, 2015

19

Multiregional Clinical Trials: Japanese Perspective on Drug Development Strategy and Sample Size for Japanese Subjects

Ando, Yuki, Uyama, Yoshiaki

Journal:

Journal of Biopharmaceutical Statistics

Year:

2012

Language:

english

File:

PDF, 360 KB

english, 2012

20

Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians

Hasunuma, Tomoko, Tohkin, Masahiro, Kaniwa, Nahoko, Jang, In-Jin, Yimin, Cui, Kaneko, Masaru, Saito, Yoshiro, Takeuchi, Masahiro, Watanabe, Hiroshi, Yamazoe, Yasushi, Uyama, Yoshiaki, Kawai, Shinichi

Journal:

British Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 976 KB

english, 2016

21

The MIHARI project: establishing a new framework for pharmacoepidemiological drug safety assessments by the Pharmaceuticals and Medical Devices Agency of Japan

Ishiguro, Chieko, Takeuchi, Yoshinori, Uyama, Yoshiaki, Tawaragi, Tomiko

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2016

Language:

english

File:

PDF, 382 KB

english, 2016

22

Inhibition by calponin of isometric force in demembranated vascular smooth muscle strips: the critical role of serine-175

UYAMA, Yoshiaki, IMAIZUMI, Yuji, WATANABE, Minoru, WALSH, Michael P.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 631 KB

english, 1996

23

Determination of the Structure of [1- 13 C]Glycine-[ 15 N]Alanine Double Labeled Bombyx mori Silk Fibroin Fibers Using Solid State 15 N NMR

Asakura, Tetsuo, Demura, Makoto, Hiraishi, Yoshiaki, Ogawa, Katsuaki, Uyama, Atsuo

Journal:

Chemistry Letters

Year:

1994

File:

PDF, 399 KB

1994

24

Contribution of pharmacology for new drug application in Japan.

SUZUKI-NISHIMURA, Tamiko, TOYOSHIMA, Satoshi, UYAMA, Yoshiaki, YAMADA, Hiroaki, HOSOKI, Rumiko, FUJIMORI, Kannosuke, NAGAO, Taku

Journal:

Folia Pharmacologica Japonica

Year:

2002

File:

PDF, 70 KB

2002

25

Similarities and Differences between US and Japan as to Pharmacogenomic Biomarker Information in Drug Labels

Otsubo, Yasuto, Asahina, Yasuko, Noguchi, Atsushi, Sato, Yumiko, Ando, Yuki, Uyama, Yoshiaki

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 357 KB

english, 2012

26

Current Status and Open Issues Concerning Global Clinical Trials (GCTs) in Japan and East Asia

Miyazaki, Koichi, Sato, Yasunori, Hanaoka, Hideki, Uyama, Yoshiaki

Journal:

Clinical and Translational Science

Year:

2017

Language:

english

File:

PDF, 595 KB

english, 2017

27

Clarifying the Discussion Points in New Drug Application Reviews for Approval in Japan by a Government Advisory Council

Hattori, Yasuyuki, Hanaoka, Hideki, Uyama, Yoshiaki

Journal:

Therapeutic Innovation & Regulatory Science

Year:

2017

Language:

english

File:

PDF, 635 KB

english, 2017

28

Lower proportion of spontaneous adverse event reports for generic drugs by comparison with original branded drugs at the post-market stage in Japan

Takami, Akina, Hirata, Kaori, Ishiguro, Chieko, Hanaoka, Hideki, Uyama, Yoshiaki

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 286 KB

english, 2018

29

Population/regional differences in efficacy of three drug categories (antidiabetic, respiratory, and psychotropic agents) among East Asians: A retrospective study based on multi-regional clinical trials

Sai, Kimie, Yoshida, Akiomi, Hanatani, Tadaaki, Imatoh, Takuya, Takeuchi, Masahiro, Narukawa, Mamoru, Watanabe, Hiroshi, Uyama, Yoshiaki, Saito, Yoshiro

Journal:

British Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.98 MB

english, 2019

30

1．The Achievements and Future Directions of MIHARI Project

ISHIGURO, Chieko, TAKEUCHI, Yoshinori, YAMADA, Kaori, KOMAMINE, Maki, UYAMA, Yoshiaki

Journal:

Japanese Journal of Pharmacoepidemiology/Yakuzai ekigaku

Year:

2015

File:

PDF, 1.07 MB

2015

31

Identification of gastrointestinal perforation based on ICD‐10 code in a Japanese administrative medical information database and associated drug exposure risk factors

Tanigawa, Masatoshi, Kataoka, Yoko, Kishino, Takayoshi, Kohama, Mei, Uyama, Yoshiaki, Suzuki, Yasuyuki, Yokoi, Hideto

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2019

Language:

english

File:

PDF, 772 KB

english, 2019

32

The importance of a regulatory science approach for better pharmaceutical regulation

Uyama, Yoshiaki

Journal:

Translational and Regulatory Sciences

Year:

2019

Language:

english

File:

PDF, 800 KB

english, 2019

33

[IEEE 2019 IEEE Intl Conf on Dependable, Autonomic and Secure Computing, Intl Conf on Pervasive Intelligence and Computing, Intl Conf on Cloud and Big Data Computing, Intl Conf on Cyber Science and Technology Congress (DASC/PiCom/CBDCom/CyberSciTech) - Fukuoka, Japan (2019.8.5-2019.8.8)] 2019 IEEE Intl Conf on Dependable, Autonomic and Secure Computing, Intl Conf on Pervasive Intelligence and Computing, Intl Conf on Cloud and Big Data Computing, Intl Conf on Cyber Science and Technology Congress (DASC/PiCom/CBDCom/CyberSciTech) - A Dynamic System for Forming Convoys Consisting of Connected Vehicles

Uyama, Kazuki, Inoue, Shinji, Kakuda, Yoshiaki

Year:

2019

File:

PDF, 1.34 MB

2019

34

Characteristics on Drug Safety Measures in Japan Stratified by System Organ Classes and Therapeutic Categories in Relation to the Approval Date

Hiramatsu, Ayaka, Hanaoka, Hideki, Uyama, Yoshiaki

Journal:

Therapeutic Innovation & Regulatory Science

Year:

2020

File:

PDF, 1.10 MB

2020

35

Points to consider for implementation of the ICH E17 guideline: learning from past multiâregional clinical trials (MRCTs) in Japan

Asano, Kunihito, Aoi, Yoko, Kamada, Shuji, Uyama, Yoshiaki, Tohkin, Masahiro

Journal:

Clinical Pharmacology & Therapeutics

Year:

2020

File:

PDF, 10.76 MB

2020